The Association of Black Cardiologists is a cosigner of the recently published 2018 ACC/AHA Guideline on Management of Blood Cholesterol, a document that was carefully crafted by the writing committee and experts in the field; and intended to inform clinical decision-making among practitioners. The significance of this document is better understood after a brief historical review of the state of guideline implementation among clinicians and the emerging perspective on guideline implementation. Clinical practice guidelines have evolved from an expert-opinion based document in years past, to a predominantly evidence-based publication designed to facilitate dissemination of the results of scientific research and progress to clinical practice.  Standardization of practice and maximization of healthy outcomes in a cost-effective manner are the anticipated goals of guideline implementation and adherence.  …